Reflux, early satiety, and the volume the stomach will accept
What scintigraphy and breath-test studies established about emptying rate, and what they did not.
Archive — March 2024
Page 3 of 5 of this archive, newest first.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
What a 25% rise in coupling-reagent prices does to a 10 mg vial
Follow the resin, not the catalogue.
VendorInvestigate result on a Hong Kong mazdutide lot lands 2.6 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
The quiet end of the consolidator trading as Meridian Freight Partners
A proper account of an operation that existed, and of what closing it cost.
The badge is about a sample. The listing is about a product.
The Journal does not treat a badge as evidence and states so wherever it reports one.
MKM declines, for the 19th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Independent analysis puts a BCH cagrilintide lot at 96.1%, against 95.2% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Aggregation: the impurity your chromatogram dissolved before it looked
We describe each pathway in enough chemical detail to explain why it is invisible to the method the trade uses, because that is the part which has practical consequences.
Thiamine and the vomiting patient
What the trials measured, which in the case of micronutrients is very little.
VendorInvestigate result on a Zhuhai semaglutide lot lands 1.1 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
What changed at QSC in March, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The quiet end of Calder Vale Peptides of Skipton
A proper account of an operation that existed, and of what closing it cost.
A shortage listing ends. 18 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Why a dead-clean sterile filter can pass pyrogen straight through
Bacterial endotoxin is a heat-stable lipopolysaccharide from the outer membrane of Gram-negative organisms. It survives sterilisation, passes a sterilising filter, and is…
Lean mass is a compartment, not a tissue
The instrument determines the answer more than the drug does, and the trade quotes the answer without naming the instrument.
Ireland declines to reimburse liraglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Qingdao export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
A shortage listing ends. 6 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Background rates, and why they matter for attribution
Rapid weight loss by any means raises gallstone risk. Separating that from a direct drug effect requires a comparator, and the trials have one.
LAL, kinetic chromogenic, recombinant factor C: three ways to the same figure
Bacterial endotoxin is a heat-stable lipopolysaccharide from the outer membrane of Gram-negative organisms. It survives sterilisation, passes a sterilising filter, and is…
What a 23% rise in coupling-reagent prices does to a 15 mg vial
Follow the resin, not the catalogue.
What the new Italy guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
From the floor in Qingdao: 5 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Why "muscle-sparing" is a marketing term and not a measurement
The gap between a defensible recommendation and a confident one is where most of the harm in this subject lives.
Site selection when the tissue has already changed
A rotation scheme that is too complicated will not be followed. We describe the simple ones that are.
The specification sheet says 500,000. The report says conforms.
Calibration drift is real, unremarkable, and the reason serious laboratories run internal standards.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
GGPeps declines, for the 15th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Ireland declines to reimburse liraglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
South Africa caps semaglutide prescribing to 8 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
SURPASS-3 was built to answer the stopping question, and it did
What was withdrawn, from whom, after how long, and what was measured afterwards.
India pharmacy body issues counselling standards for tirzepatide initiation
The evidence base is thin and the document says so, which is to its credit.
SURMOUNT-1 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Low endotoxin recovery: the interference nobody looks for
The masking phenomenon known as low endotoxin recovery means a formulation can return a clean result while containing endotoxin the assay cannot see.
Percentage of loss, absolute kilograms, and the sleight of hand between them
A substudy powered to describe a mean is not a substudy powered to detect a clinically meaningful individual change.