The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
Archive — November 2024
Page 3 of 5 of this archive, newest first.
What the placebo arms of the withdrawal trials actually tell us
Three randomised withdrawal designs have tested what happens when treatment stops. Their results are consistent and they are consistently misreported.
The reproducible spectrum: the single most useful thing a report can carry
None of what a checkable identity statement requires is commercially sensitive, and all of it is known to whoever produced the document.
Canada pharmacy body issues counselling standards for semaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
Calder Vale Peptides of Skipton enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
South Korea declines to reimburse tirzepatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Tolerability is the ceiling, and the ceiling is personal
Roughly four to seven per cent of trial participants discontinued for adverse events, mostly gastrointestinal, mostly during escalation. That is the empirical size of the…
The shortage years, and what they taught about interruption
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
What the new Saudi Arabia guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
From the floor in Hangzhou: 6 posters, one theme
Reported from the sessions, and from the two hours afterwards.
VendorInvestigate result on a Guangzhou retatrutide lot lands 3.9 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
What changed at FGP in November, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Twenty-eight days is a number from somebody else’s product
Bacteriostatic water contains benzyl alcohol at 0.9 per cent, which inhibits microbial growth in a preserved multiple-dose presentation. It does not sterilise a contaminated…
Sarcopenia is a diagnosis, not a synonym for losing lean mass
The rule that a quarter of weight lost is lean tissue has been in textbooks for decades and does not survive close reading.
The reviewer, the approver, and why regulated documents carry two names
What the Journal asks when a document arrives unsigned, and what the answers have been.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
A supplier suspends shipping to India after 4 consecutive customs detentions
The route did not close because of a rule about peptides.
What changed at SWB in November, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Switzerland caps semaglutide prescribing to 8 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Reproducibility, measured rather than assumed
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
From the floor in Wuhan: 19 posters, one theme
Reported from the sessions, and from the two hours afterwards.
The 30-day notice: how a compounding wind-down works in Argentina
The document is four pages. Three of them are about dates.
TFC declines, for the 8th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Japan declines to reimburse exenatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Everything a buyer assumes has been checked, ranked by whether it has
A purity figure is silent on peptide content, on water, on counter-ion, on sterility, on endotoxin and on stability. Each of those silences has a price attached.
The interventions with trial support, and the much longer list without
We separate what is supported, what is reasonable, and what is folklore, and we do not pretend the boundaries are crisp.
Australia declines to reimburse semaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
SGN declines, for the 24th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What changed at WWB in November, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Turkey caps liraglutide prescribing to 12 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Vitamin D, adiposity, and a volume-of-distribution problem
A monitoring schedule requires evidence about incidence. For this population, that evidence does not exist.
Reproducibility, measured rather than assumed
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
The out-of-range flag is a statistical convention with a printer attached
A flag is a probability statement about a population. It is not a statement about the person holding the printout.
What changed at SWB in November, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What the new Ireland guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Inspectors cite the online reseller trading as Adamant Research Supply over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Randomised withdrawal is the cleanest design in this field and the least discussed
Three randomised withdrawal designs have tested what happens when treatment stops. Their results are consistent and they are consistently misreported.
STEP 4 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
A supplier suspends shipping to Nigeria after 20 consecutive customs detentions
The route did not close because of a rule about peptides.
The quiet end of the online reseller trading as Adamant Research Supply
A proper account of an operation that existed, and of what closing it cost.