Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
The archive — 2025
Page 67 of 68 of this archive, newest first.
SURMOUNT-4 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
TFC declines, for the 15th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The retest date and the expiry date are not the same document
We asked twenty companies three questions about stability data and print every answer, refusal and non-response.
Calder Vale Peptides of Skipton closes after 12 years
A proper account of an operation that existed, and of what closing it cost.
Spain health authority warns on falsified dulaglutide pens
Reported from the analysis, not from a warning notice.
SURPASS-4 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
A shortage listing ends. 16 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
Oxidation, and the peroxide that came in with the surfactant
We describe each pathway in enough chemical detail to explain why it is invisible to the method the trade uses, because that is the part which has practical consequences.
The dose that got you here and the dose that keeps you here
Every withdrawal trial compared full dose against nothing. The clinically interesting comparison — full dose against a reduced one — has not been randomised.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at GL Biochem in January, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What the new Spain guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Everything a buyer assumes has been checked, ranked by whether it has
The absences are not concealment. They are the form the trade settled on, and no buyer has ever objected.
Holidays, surgery, sickness: interruption in practice
Supply interruption is the commonest cause of unplanned re-titration in this market, and it is almost never framed that way.
What a 32% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
South Africa caps tirzepatide prescribing to 17 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
A supplier suspends shipping to New Zealand after 3 consecutive customs detentions
The route did not close because of a rule about peptides.
At 214 nanometres you see every peptide bond. At 280 you see three residues.
Area per cent silently assumes that every species in the sample absorbs as strongly per unit mass as the parent. For peptide impurities that assumption is usually wrong, and…
When to stop escalating and when to stop entirely
We set out the questions that distinguish a symptom to manage from a dose to change.
FGP declines, for the 15th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Japan declines to reimburse tirzepatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
What the new Nigeria guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
The change that weighs nothing at all
Deamidation adds 0.98 daltons. On a low-resolution instrument at incretin molecular weights, that is inside the noise.
Percentage of loss, absolute kilograms, and the sleight of hand between them
The trials measured mass. Nobody measured whether the participants got weaker.
The supply gap as a clinical event
Why the reason for stopping changes what happens afterwards.
The consolidator trading as Meridian Freight Partners closes after 21 years
A proper account of an operation that existed, and of what closing it cost.
The quiet end of the consolidator trading as Meridian Freight Partners
A proper account of an operation that existed, and of what closing it cost.