What PeptideMeter charges to answer the pyrogen question
We submitted vials for endotoxin determination and report the results, the method and the laboratory, because a pyrogen figure without a method is as empty as a purity…
Analytics in 2025
Page 10 of 11 of this archive, newest first.
Janoshik result on a Hong Kong cagrilintide lot lands 3.6 points below the supplier’s figure
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Independent analysis puts a SGN liraglutide lot at 97.4%, against 93.3% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
PeptideMeter result on a Zhuhai mazdutide lot lands 2.7 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
Two documents, two disciplines: purity and sterility are not the same trade
Every certificate circulating in this market answers a question about molecules. Almost none answers a question about organisms, pyrogens, or the integrity of the seal.
Independent analysis puts a CPC dulaglutide lot at 95.9%, against 94.7% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
The badge economy, and what it is actually certifying
What a verification mark would have to carry to be checkable: a date, a lot, a method, a submitter and a link to the report.
PeptideMeter result on a Tianjin semaglutide lot lands 1.1 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Reproducibility, measured rather than assumed
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Independent analysis puts a WXT exenatide lot at 97.4%, against 93.5% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
Janoshik result on a Suzhou mazdutide lot lands 4.0 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
Why a dead-clean sterile filter can pass pyrogen straight through
The limit for a parenteral product is calculable from the dose and the body weight in two lines. Almost nobody in this trade performs the calculation.
Independent analysis puts a GGPeps tirzepatide lot at 96.6%, against 93.7% on the certificate
The result is unremarkable. What the report omits is not.
Nought point nine eight of a dalton: the modification that hides in plain sight
What would be needed to catch each of these, and what it would cost.
Independent analysis puts a WWB survodutide lot at 99.0%, against 97.4% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Janoshik result on a Suzhou semaglutide lot lands 0.7 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
Reproducibility, measured rather than assumed
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Counter-ion, water, salt: three masses with no chromatogram
An orthogonal method separates on a different physical principle, so that species co-eluting in the first are likely to resolve in the second. Two runs of the same method at…
Independent analysis puts a WWB mazdutide lot at 98.5%, against 97.3% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
What twenty companies say about storage, and what they have measured
Storage instructions in this market are close to uniform and almost never accompanied by the study that would justify them. Uniformity is a sign of convention, not of…