What a 1 mL syringe does that a 0.3 mL syringe does not
The graduation interval differs between barrel sizes, and a 1 mL barrel is frequently marked in two-unit steps. Reading one as though it were marked in single units halves…
Patient Notes in 2024
Page 5 of 10 of this archive, newest first.
The supply gap as a clinical event
Why the reason for stopping changes what happens afterwards.
Ireland pharmacy body issues counselling standards for liraglutide initiation
The evidence base is thin and the document says so, which is to its credit.
Do you need the top of the ladder?
A plateau at an intermediate dose and a plateau at the maximum dose look identical from the outside and mean different things.
What the new the United Arab Emirates guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
What STEP 5 tells us about maintenance, and what it does not
Dose reduction is not withdrawal, and the trials that tested withdrawal cannot be read as testing it.
What the new Singapore guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Canada pharmacy body issues counselling standards for exenatide initiation
The evidence base is thin and the document says so, which is to its credit.
What the new Brazil guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Why "muscle-sparing" is a marketing term and not a measurement
The rule that a quarter of weight lost is lean tissue has been in textbooks for decades and does not survive close reading.
What the new Ireland guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Gallstones during rapid weight loss: drug, or weight loss?
Pancreatitis is rare, was adjudicated in the outcome programmes, and did not show the imbalance early case reports suggested.
Brazil pharmacy body issues counselling standards for dulaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
The advice is mostly reasonable. The certainty is not earned.
Almost every practical recommendation in circulation was established in a population that does not resemble the people now following it.
What the new Argentina guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
The convention nobody explains before handing over the vial
Dead space in the needle hub is a real and calculable loss, and it matters more at small volumes than anybody expects.
Why people actually stop, in the order they actually stop
The trials studied planned withdrawal. Almost nobody stops that way.
Escalating onto a rising curve
What the published pharmacokinetics permit, what the labels state, and where the two diverge.
What the new Canada guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Reading a barrel: the graduation that is not the one you think
We work through the arithmetic in full, because it is short, and because the errors it prevents are order-of-magnitude errors.