Switzerland pharmacy body issues counselling standards for semaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 12 of 25 of this archive, newest first.
The evidence base is thin and the document says so, which is to its credit.
The receptor populations that produce satiety and the ones that produce nausea overlap substantially. That is why the ceiling of this drug class is where it is, and it is…
A single drug producing both constipation and diarrhoea looks contradictory until the motility data is read properly.
The evidence base is thin and the document says so, which is to its credit.
Every withdrawal trial compared full dose against nothing. The clinically interesting comparison — full dose against a reduced one — has not been randomised.
The evidence base is thin and the document says so, which is to its credit.
Dose reduction is not withdrawal, and the trials that tested withdrawal cannot be read as testing it.
The evidence base is thin and the document says so, which is to its credit.
We work the arithmetic out in full, because it is arithmetic and it is short.
The evidence base is thin and the document says so, which is to its credit.
A small number of serious gastrointestinal events occur in people taking these drugs. Distinguishing them from the expected effect profile is the most consequential…
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
Sharps disposal is a legal obligation in most jurisdictions and a safety obligation everywhere. Household waste is not a route.
The evidence base is thin and the document says so, which is to its credit.
What was withdrawn, from whom, after how long, and what was measured afterwards.
A twelve-analyte panel in a perfectly healthy person has roughly even odds of producing at least one flagged result.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.