Oxidation, and the peroxide that came in with the surfactant
The sequence predicts the failure mode. A methionine predicts oxidation; an asparagine followed by a glycine predicts deamidation; a cysteine predicts disulphide scrambling.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Reporting from across the Journal that names GenScript Biotech Corporation, together with the correspondence this desk has had with the company about it. The dossier itself — the testing record, the correspondence log, the ordering box and the reader reports — is here. The company sells directly at genscriptpeptides.com, a labelled and nofollowed link the Journal is paid nothing for; read the record before you use it.
The sequence predicts the failure mode. A methionine predicts oxidation; an asparagine followed by a glycine predicts deamidation; a cysteine predicts disulphide scrambling.
We asked twenty companies three questions about stability data and print every answer, refusal and non-response.
Reported from the analysis, not from a warning notice.
Reported from the analysis, not from a warning notice.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Reported from the analysis, not from a warning notice.
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
The route did not close because of a rule about peptides.