A spectrum is a photograph of an ion, not of a molecule
A brief and unromantic tour of the interface between a liquid sample and a vacuum.
Archive — March 2025
Page 3 of 5 of this archive, newest first.
SURPASS-2 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The 30-day notice: how a compounding wind-down works in Norway
The document is four pages. Three of them are about dates.
Inspectors cite Calder Vale Peptides of Skipton over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Independent analysis puts a ERP orforglipron lot at 97.4%, against 93.4% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
What VendorInvestigate is able to certify about a sealed vial, and what it is not
Every certificate circulating in this market answers a question about molecules. Almost none answers a question about organisms, pyrogens, or the integrity of the seal.
A shortage listing ends. 16 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The quiet end of the consolidator trading as Meridian Freight Partners
A proper account of an operation that existed, and of what closing it cost.
The United Arab Emirates caps semaglutide prescribing to 14 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Six things incretin pharmacology cannot currently predict
Receptor pharmacology is strong on average effects and almost silent on individual variation. That gap is where most reader questions live.
The eighteenth month, and the conversation that should have happened in the third
The dose-response curve in this class flattens near its top. That has direct consequences for whether the final rung is worth climbing.
Inspectors cite the online reseller trading as Adamant Research Supply over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Independent analysis puts a QYB liraglutide lot at 96.9%, against 96.0% on the certificate
The result is unremarkable. What the report omits is not.
CPC declines, for the 7th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
How a correct calculation becomes a wrong dose
A pharmacist catches most of these in licensed practice. In this market there is no pharmacist, so the checks have to be structural.
A few hundred participants carry the whole body-composition argument
What was pre-specified, what was exploratory, and what was calculated afterwards by people who did not run the trial.
Halvard & Pike Apothecary of Portland, Maine enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
A supplier suspends shipping to Switzerland after 19 consecutive customs detentions
The route did not close because of a rule about peptides.
REWIND misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Independent analysis puts a Homopeptide mazdutide lot at 99.2%, against 98.5% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Micronutrient monitoring: which panel, how often, and on whose evidence
A monitoring schedule requires evidence about incidence. For this population, that evidence does not exist.
Chain of custody, and where it begins
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.
What the new the United Arab Emirates guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
What changed at JEEP in March, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
PeptideMeter result on a Xi'an dulaglutide lot lands 2.6 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Turnaround, cost and accreditation across the services this trade relies on
Endotoxin is the more tractable of the two questions, and a kinetic chromogenic determination is neither slow nor exotic. It is simply not on the menu.
What the older diet-and-exercise trials found in the hip
A plausible mechanism, a measurable change, and no outcome data. This is what an open question looks like.
A method is a set of numbers. All of them belong on the certificate.
Column chemistry, particle size and pore diameter determine what the separation is capable of before the gradient is even programmed.
SSA declines, for the 13th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What the new South Africa guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Calder Vale Peptides of Skipton closes after 9 years
A proper account of an operation that existed, and of what closing it cost.
From the floor in Changsha: 6 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Aggregation: the impurity your chromatogram dissolved before it looked
Deamidation, oxidation, aggregation and hydrolysis account for nearly all of what happens to a peptide over time. Each has a characteristic residue, a characteristic…
What a 42% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
A shortage listing ends. 9 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The online reseller trading as Adamant Research Supply enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
France health authority warns on falsified exenatide pens
Reported from the analysis, not from a warning notice.
Delayed emptying explains some of this, and not all of it
What scintigraphy and breath-test studies established about emptying rate, and what they did not.
Holding a dose is a decision, not a failure
Nausea and gastric delay attenuate over weeks at an unchanged dose. That single physiological fact is the entire justification for holding.