Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 3 of 5 of this archive, newest first.
Reported from the analysis, not from a warning notice.
Delayed gastric emptying is a mechanism that becomes an adverse effect above a threshold. It is not a complication in the ordinary sense.
The instrument determines the answer more than the drug does, and the trade quotes the answer without naming the instrument.
Follow the resin, not the catalogue.
Efficacy was never the question in this appraisal. Duration of treatment was.
Reported from the sessions, and from the two hours afterwards.
Almost every figure in circulation about tolerability comes from six publications. This is what they say.
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Reported from the analysis, not from a warning notice.
Reported from the sessions, and from the two hours afterwards.
The route did not close because of a rule about peptides.
This piece takes the measurement apart into the decisions it is made of, because each decision moves the answer.
A plausible mechanism, a measurable change, and no outcome data. This is what an open question looks like.
The arithmetic of significant figures, applied to a document that routinely reports four of them.
Reported from the analysis, not from a warning notice.
Follow the resin, not the catalogue.
The evidence base is thin and the document says so, which is to its credit.
A proper account of an operation that existed, and of what closing it cost.
Every withdrawal trial compared full dose against nothing. The clinically interesting comparison — full dose against a reduced one — has not been randomised.
Reported from the analysis, not from a warning notice.
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The evidence base is thin and the document says so, which is to its credit.
The observation that closes a facility is rarely the dramatic one.
A manufacturer’s certificate is a self-declaration. An accredited laboratory’s report is a third-party measurement. The trade prints both under one heading.
What was pre-specified, what was exploratory, and what was calculated afterwards by people who did not run the trial.
Reported from the sessions, and from the two hours afterwards.
The route did not close because of a rule about peptides.
The document is four pages. Three of them are about dates.
Reported from the sessions, and from the two hours afterwards.
HbA1c integrates roughly three months of glycaemia with the most recent weeks weighted most heavily. Almost every misreading of it is a misreading of that weighting.
A manufacturer’s certificate is a self-declaration. An accredited laboratory’s report is a third-party measurement. The trade prints both under one heading.
The argument for a baseline panel is that it makes every subsequent result interpretable. The argument against frequent monitoring is that noise accumulates faster than…
The evidence base is thin and the document says so, which is to its credit.
Follow the resin, not the catalogue.
The report states the gradient, the wavelength and the integration threshold, which is more than most.
The receptor populations that produce satiety and the ones that produce nausea overlap substantially. That is why the ceiling of this drug class is where it is, and it is…
The document is four pages. Three of them are about dates.
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
A reminder that a purity figure is the output of a method, and that methods differ.