The quiet end of Halvard & Pike Apothecary of Portland, Maine
A proper account of an operation that existed, and of what closing it cost.
The archive — 2025
Page 3 of 68 of this archive, newest first.
The supply gap as a clinical event
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
Nought point nine eight of a dalton: the modification that hides in plain sight
Deamidation adds 0.98 daltons. On a low-resolution instrument at incretin molecular weights, that is inside the noise.
WWB declines, for the 17th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Singapore health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
From the floor in Nantong: 9 posters, one theme
Reported from the sessions, and from the two hours afterwards.
What the new Norway guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
What the liraglutide schedule assumes about a person it has never met
The four-week step exists because four to five weeks is approximately how long a once-weekly drug takes to stop rising at a fixed dose. That is a good reason, and it is not…
Who chose the vial that was tested?
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
The slide that was not in the abstract
Reported from the sessions, and from the two hours afterwards.
A shortage listing ends. 11 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The upper rungs, ranked by evidence
We looked at what the dose-ranging data supports about going higher, and it is thinner and less flattering than the market assumes.
A supply gap is a pharmacological event
The convention — resume lower, re-escalate — is not caution. It follows directly from the elimination half-life.
The relabeller trading as Vantris Bio enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
The 26-day notice: how a compounding wind-down works in South Korea
The document is four pages. Three of them are about dates.
TRIUMPH-1 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Sterility is not a percentage, which is the whole difficulty
Purity, content, identity, sterility and endotoxin are five separate determinations. A single sheet of paper carrying one of them is not evidence about the other four.
The submitted sample: the weakest link in the whole system
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.
Mean kinetic temperature is not the average temperature
A single-use logger records the air adjacent to itself at a fixed interval. Where it sits in the package, and how often it samples, determine what it can possibly detect.
The relabeller trading as Vantris Bio closes after 11 years
A proper account of an operation that existed, and of what closing it cost.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What a 26% rise in coupling-reagent prices does to a 10 mg vial
Follow the resin, not the catalogue.
A shortage listing ends. 18 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The out-of-range flag is a statistical convention with a printer attached
The arithmetic of the reference change value, worked for the analytes that matter here.
Independent analysis puts a WWB tirzepatide lot at 98.7%, against 94.6% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
GL Biochem declines, for the 17th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
The skeleton responds to load, and load is falling
Density is a proxy for strength and an imperfect one, particularly when soft-tissue thickness over the measurement site is changing.