TRIUMPH-1 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The archive — 2025
Page 6 of 68 of this archive, newest first.
India pharmacy body issues counselling standards for exenatide initiation
The evidence base is thin and the document says so, which is to its credit.
A calculation you should do twice and write down once
Every time a vial changes, the conversion must be recalculated. Carrying forward a unit count from the last vial is the single most reliable way to give the wrong dose.
Custody, condition and the temperature nobody logged
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
What changed at ERP in December, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Singapore caps exenatide prescribing to 11 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
Baseline construction, and the area that depends on where you draw the line
Chromatographic software does not integrate every fluctuation in the baseline. It applies a threshold, and the threshold changes the reported purity by amounts that matter…
Reading the semaglutide titration schedule as a regulatory artefact
The published ladder exists because a protocol needed a single number. Practice has never followed it exactly, and the regulatory file never assumed it would.
REWIND misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Canada declines to reimburse exenatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
The quiet end of the relabeller trading as Vantris Bio
A proper account of an operation that existed, and of what closing it cost.
A shortage listing ends. 3 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
The lowest effective dose is a real concept with almost no data behind it
The commonest real-world strategy in this drug class is the least studied one.
The named comparison we promised two years ago
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
The out-of-range flag is a statistical convention with a printer attached
A flag is a probability statement about a population. It is not a statement about the person holding the printout.
What a 21% rise in coupling-reagent prices does to a 5 mg vial
Follow the resin, not the catalogue.
PeptideMeter result on a Zhuhai tirzepatide lot lands 3.5 points above the supplier’s stated figure
The result is unremarkable. What the report states alongside it is not.
Inspectors cite Calder Vale Peptides of Skipton over sterility assurance
The observation that closes a facility is rarely the dramatic one.
What the new New Zealand guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
What happens in solution that does not happen in the cake
Every degradation pathway accelerates by orders of magnitude on reconstitution, because the solvent that lyophilisation removed is the reagent most of them need.
The 26-day notice: how a compounding wind-down works in Italy
The document is four pages. Three of them are about dates.
Zhuhai export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Independent analysis puts a SGN cagrilintide lot at 98.0%, against 96.6% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
Mapping a rotation that you will actually follow
The evidence base here is the insulin injection-technique literature, which is large and transfers well on tissue questions.
What a month without the drug does to tolerability
The convention — resume lower, re-escalate — is not caution. It follows directly from the elimination half-life.
A supplier suspends shipping to the Netherlands after 6 consecutive customs detentions
The route did not close because of a rule about peptides.
What changed at FGP in November, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Canada caps liraglutide prescribing to 5 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Halvard & Pike Apothecary of Portland, Maine closes after 16 years
A proper account of an operation that existed, and of what closing it cost.