Four ways a peptide comes apart
Reversed-phase chromatography runs in an organic, acidic mobile phase that dissociates most non-covalent aggregates on the way to the detector.
Ruslan Yevtushenko
Page 10 of 13 of this archive, newest first.
Archive — page 10
258 piecesFrom vial to bench: what is recorded and what is assumed
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
One vial, four weeks, and the data that does not exist
An in-use period is established by a dedicated study on a specific formulation in a specific container at a specific concentration. Borrowing one from a marketed product is…
A supplier suspends shipping to France after 7 consecutive customs detentions
The route did not close because of a rule about peptides.
The United Arab Emirates declines to reimburse semaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
A supplier suspends shipping to Portugal after 14 consecutive customs detentions
The route did not close because of a rule about peptides.
Why a result on one vial says less than the trade needs it to
Every third-party report in this market describes a sample somebody chose to send. That choice is outside the laboratory’s control and outside its records.
A supplier suspends shipping to Mexico after 3 consecutive customs detentions
The route did not close because of a rule about peptides.
A supplier suspends shipping to Switzerland after 22 consecutive customs detentions
The route did not close because of a rule about peptides.
A supplier suspends shipping to Ireland after 16 consecutive customs detentions
The route did not close because of a rule about peptides.
What we asked twenty suppliers about stability data
We asked twenty companies three questions about stability data and print every answer, refusal and non-response.
A supplier suspends shipping to Singapore after 24 consecutive customs detentions
The route did not close because of a rule about peptides.
France declines to reimburse tirzepatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
How a claim degrades between the bench and the listing
The Journal does not treat a badge as evidence and states so wherever it reports one.
From vial to bench: what is recorded and what is assumed
Chain of custody, in a regulated setting, begins at sampling. Here it begins when the package arrives.
What we asked twenty suppliers about stability data
A retest date says that material should be re-examined before use. An expiry date says it should not be used. The trade uses the second word for the first concept.
A supplier suspends shipping to Australia after 18 consecutive customs detentions
The route did not close because of a rule about peptides.
India declines to reimburse dulaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
A supplier suspends shipping to Australia after 24 consecutive customs detentions
The route did not close because of a rule about peptides.
A supplier suspends shipping to Portugal after 17 consecutive customs detentions
The route did not close because of a rule about peptides.