What the new India guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 5 of 13 of this archive, newest first.
The evidence base is thin and the document says so, which is to its credit.
The recommendation survives scrutiny. The reasoning offered for it frequently does not.
The dose-response curve in this class flattens near its top. That has direct consequences for whether the final rung is worth climbing.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
What the published pharmacokinetics permit, what the labels state, and where the two diverge.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
The two ionisation techniques in general use produce different charge distributions, different adducts and different failure modes. Certificates almost never say which was…
The evidence base is thin and the document says so, which is to its credit.
The insulin injection-technique literature is large, well conducted and directly transferable on questions of depth and tissue. We say where it stops transferring.
The evidence base is thin and the document says so, which is to its credit.
The evidence base is thin and the document says so, which is to its credit.
A small number of serious gastrointestinal events occur in people taking these drugs. Distinguishing them from the expected effect profile is the most consequential…
The insulin injection-technique literature is large, well conducted and directly transferable on questions of depth and tissue. We say where it stops transferring.
The evidence base is thin and the document says so, which is to its credit.
What the trials measured was continuation against withdrawal. What patients want to know is continuation at a lower dose, and that study has largely not been done.