Norway declines to reimburse semaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
The Ledger in 2024
Page 4 of 11 of this archive, newest first.
The lead-in, the randomisation, and the year that followed
The regain trajectories, arm by arm, with the estimands named.
Why a result on one vial says less than the trade needs it to
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
The dose that got you here and the dose that keeps you here
The commonest real-world strategy in this drug class is the least studied one.
Norway declines to reimburse exenatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
South Korea caps tirzepatide prescribing to 19 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Brazil caps semaglutide prescribing to 10 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
A tested vial is evidence about a vial
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
Japan caps liraglutide prescribing to 23 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Portugal declines to reimburse tirzepatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Canada caps dulaglutide prescribing to 5 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Singapore caps tirzepatide prescribing to 15 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Ireland declines to reimburse dulaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Six words a verification badge would need to mean anything
What a verification mark would have to carry to be checkable: a date, a lot, a method, a submitter and a link to the report.
New Zealand caps dulaglutide prescribing to 17 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
Sweden declines to reimburse tirzepatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
Maintenance dosing: what is licensed, what is practised, and what is evidenced
A survey of the maintenance evidence, which is shorter than the survey of the withdrawal evidence.
Maintenance dosing: what is licensed, what is practised, and what is evidenced
Dose reduction is not withdrawal, and the trials that tested withdrawal cannot be read as testing it.
From vial to bench: what is recorded and what is assumed
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
Argentina caps liraglutide prescribing to 5 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.