What happens in solution that does not happen in the cake
Every degradation pathway accelerates by orders of magnitude on reconstitution, because the solvent that lyophilisation removed is the reagent most of them need.
Certificates of analysis
Page 13 of 51 of this archive, newest first.
Independent analysis puts a SGN cagrilintide lot at 98.0%, against 96.6% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
What changed at FGP in November, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Same material, different gradients, different answers
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Independent analysis puts a GL Biochem semaglutide lot at 97.8%, against 94.6% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
The United Arab Emirates health authority warns on falsified exenatide pens
Reported from the analysis, not from a warning notice.
The badge is about a sample. The listing is about a product.
Every step between the laboratory report and the product page removes information, and the badge is the last step.
What changed at SWB in November, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
BCH names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Singapore health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
Why a 0.036-dalton difference is the hardest number in peptide identity
Calibration drift is real, unremarkable, and the reason serious laboratories run internal standards.
Turkey health authority warns on falsified exenatide pens
Reported from the analysis, not from a warning notice.
Medutest result on a Chengdu cagrilintide lot lands 4.4 points above the supplier’s stated figure
A reminder that a purity figure is the output of a method, and that methods differ.
Independent analysis puts a FGP mazdutide lot at 98.8%, against 96.2% on the certificate
The report states the gradient, the wavelength and the integration threshold, which is more than most.
TFC names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
JEEP names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Endotoxin is not a microorganism, and killing the bacteria does not remove it
The masking phenomenon known as low endotoxin recovery means a formulation can return a clean result while containing endotoxin the assay cannot see.
How a claim degrades between the bench and the listing
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
Pore size, particle size, and why peptides need the wide pores
Ion-pairing additives sharpen peptide peaks and suppress ionisation in the mass spectrometer, which is why the purity method and the identity method are often not the same…
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.