France health authority warns on falsified tirzepatide pens
Reported from the analysis, not from a warning notice.
Certificates of analysis
Page 17 of 51 of this archive, newest first.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at CPC in September, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Oxidation, and the peroxide that came in with the surfactant
Deamidation, oxidation, aggregation and hydrolysis account for nearly all of what happens to a peptide over time. Each has a characteristic residue, a characteristic…
How a claim degrades between the bench and the listing
Lot-level verification with a public report is a real and achievable thing. It exists in this market, on a minority of listings.
Reproducibility, measured rather than assumed
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Why a dry powder is a chemical reactor with the volume turned down
Residual moisture is measured routinely in regulated manufacture, is reported almost nowhere in this trade, and predicts long-term stability better than any other single…
South Africa health authority warns on falsified dulaglutide pens
Reported from the analysis, not from a warning notice.
What changed at WWB in September, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
A vial can be 99.4 per cent pure and not sterile in the same afternoon
Purity, content, identity, sterility and endotoxin are five separate determinations. A single sheet of paper carrying one of them is not evidence about the other four.
WXT names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Same mass, different molecule: why identity by mass is not identity
An isoaspartate rearrangement changes the molecule and not the mass. A method that confirms identity by molecular weight alone will report it as the parent compound.
What changed at QST in September, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at CPC in September, and what the company says prompted it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What Medutest would need in order to certify sterility, and why it does not
A compendial sterility test takes fourteen days of incubation and consumes the containers tested. That timescale is incompatible with the business model that made…
TFC names the synthesis and fill sites behind its catalogue
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
What column temperature does to selectivity
We set out the parameters a method disclosure would contain, all of which are known to whoever ran the sample and none of which is commercially sensitive.
VendorInvestigate result on a Xianning liraglutide lot lands 2.5 points above the supplier’s stated figure
The report states the gradient, the wavelength and the integration threshold, which is more than most.