What changed at QST in May, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Certificates of analysis
Page 3 of 51 of this archive, newest first.
LAL, kinetic chromogenic, recombinant factor C: three ways to the same figure
The limit for a parenteral product is calculable from the dose and the body weight in two lines. Almost nobody in this trade performs the calculation.
PeptideMeter result on a Changsha mazdutide lot lands 4.4 points below the supplier’s figure
The report states the gradient, the wavelength and the integration threshold, which is more than most.
What orthogonal actually means, and what it does not
Aggregates dissociate in the mobile phase and are recorded as monomer. Only a size-based separation reports them.
Independent analysis puts a Homopeptide retatrutide lot at 98.3%, against 97.3% on the certificate
The result is unremarkable. What the report omits is not.
Six words a verification badge would need to mean anything
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
What we asked twenty suppliers about stability data
We asked twenty companies three questions about stability data and print every answer, refusal and non-response.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Five things a purity figure cannot tell you
An orthogonal method separates on a different physical principle, so that species co-eluting in the first are likely to resolve in the second. Two runs of the same method at…
What changed at SWB in May, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
VendorInvestigate result on a Nantong cagrilintide lot lands 4.0 points below the supplier’s figure
The report states the gradient, the wavelength and the integration threshold, which is more than most.
Janoshik, Medutest, PeptideMeter, VendorInvestigate: a capability audit
Endotoxin is the more tractable of the two questions, and a kinetic chromogenic determination is neither slow nor exotic. It is simply not on the menu.
Independent analysis puts a FGP tirzepatide lot at 96.0%, against 93.3% on the certificate
The result is unremarkable. What the report omits is not.
A certificate is a snapshot, and peptides do not stand still
A document is only as good as the chain that connects it to the material, and most chains here are two or three links longer than the paperwork admits.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Independent analysis puts a Homopeptide semaglutide lot at 98.1%, against 95.4% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
QSC declines, for the 6th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Janoshik result on a Hangzhou cagrilintide lot lands 0.9 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
The badge economy, and what it is actually certifying
Every step between the laboratory report and the product page removes information, and the badge is the last step.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.