Pancreatitis, obstruction, gallbladder: three things nausea can be
A small number of serious gastrointestinal events occur in people taking these drugs. Distinguishing them from the expected effect profile is the most consequential…
April 2025
Everything filed in April 2025, the month of Volume 2, Number 4. The issue itself — cover, editor’s letter and table of contents — is here.
Janoshik result on a Nantong retatrutide lot lands 1.4 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
The quiet end of the relabeller trading as Vantris Bio
A proper account of an operation that existed, and of what closing it cost.
A supplier suspends shipping to Saudi Arabia after 6 consecutive customs detentions
The route did not close because of a rule about peptides.
The advice is mostly reasonable. The certainty is not earned.
Almost every practical recommendation in circulation was established in a population that does not resemble the people now following it.
A vial can be 99.4 per cent pure and not sterile in the same afternoon
Every certificate circulating in this market answers a question about molecules. Almost none answers a question about organisms, pyrogens, or the integrity of the seal.
Independent analysis puts a WXT exenatide lot at 96.5%, against 92.6% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
Inspectors cite the online reseller trading as Adamant Research Supply over sterility assurance
The observation that closes a facility is rarely the dramatic one.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
What a 9% rise in coupling-reagent prices does to a 10 mg vial
Follow the resin, not the catalogue.
The GLP-1 receptor is not a switch, and survodutide is not a key
What the in-vitro data supports, what it does not, and where the extrapolation to a person begins.
A document, not a test: what a certificate actually is
The header identifies the batch, the table records the tests, and the footer says who is answerable. Two of the three are usually incomplete.
What the new Saudi Arabia guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
The quiet end of the consolidator trading as Meridian Freight Partners
A proper account of an operation that existed, and of what closing it cost.
A shortage listing ends. 5 pharmacies now have a business model and no legal basis for it.
The document is four pages. Three of them are about dates.
FGP declines, for the 15th time, to name its synthesis house
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
The incretin receptors, ranked by how much we actually know about them
Selectivity, potency and efficacy are three different measurements. The trade routinely reports none of them.
The upper rungs, ranked by evidence
Where the curve flattens, what flattens with it, and what does not.
India pharmacy body issues counselling standards for semaglutide initiation
The evidence base is thin and the document says so, which is to its credit.
Xianning export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Ireland health authority warns on falsified liraglutide pens
Reported from the analysis, not from a warning notice.
From the floor in Nantong: 13 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Why purity is the cheapest number to flatter
The Journal has read several hundred certificates from twenty companies. The number is almost always there; the method behind it almost never is.
The shortage years, and what they taught about interruption
Real-world persistence figures, with their definitions stated, because the definitions are doing most of the work.
The one-quarter rule, and the paper that took it apart
Grading six widely repeated claims against the studies actually behind them.
What changed at TFC in April, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Janoshik result on a Wuhan orforglipron lot lands 4.2 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
The quiet end of the relabeller trading as Vantris Bio
A proper account of an operation that existed, and of what closing it cost.
A needle is a single-use instrument
Sharps disposal is a legal obligation in most jurisdictions and a safety obligation everywhere. Household waste is not a route.
Singapore declines to reimburse exenatide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
STEP 8 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Inspectors cite the online reseller trading as Adamant Research Supply over sterility assurance
The observation that closes a facility is rarely the dramatic one.
The 8-day notice: how a compounding wind-down works in India
The document is four pages. Three of them are about dates.
The precision question nobody puts to a body-composition report
A body-composition report gives four decimal places and no confidence interval. That is the whole difficulty in one sentence.
Mass spectrometry answers a different question, properly
The most useful single addition to any purity determination is a second separation under a different pH or on a different stationary phase, and the second-most useful is a…
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
What changed at KP in April, and what the company will not say about it
Documentation practice is the only part of vendor quality a buyer can assess before purchase.
Why summer is a documented quality problem in this trade
The route did not close because of a rule about peptides.
From the floor in Shenzhen: 9 posters, one theme
Reported from the sessions, and from the two hours afterwards.
What PeptideMeter can tell you about a vial by weighing its water
The physics of the drying cycle explains why some cakes are matte and full-volume and others are glassy discs, and why the difference is not cosmetic.