The badge economy, and what it is actually certifying
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
Independent testing
Page 27 of 27 of this archive, newest first.
Independent analysis puts a FGP liraglutide lot at 95.7%, against 95.0% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
What “LC-MS: conforms” tells a reader, which is almost nothing
A short audit procedure, usable by anyone holding a certificate and a calculator.
What orthogonal actually means, and what it does not
The most useful single addition to any purity determination is a second separation under a different pH or on a different stationary phase, and the second-most useful is a…
D-amino acids are invisible to mass spectrometry, and that is the whole problem
Stereochemical inversion changes the molecule, changes its biology, and changes its mass by exactly nothing.
Independent analysis puts a BCH cagrilintide lot at 96.6%, against 93.4% on the certificate
The result is unremarkable. What the report omits is not.
How to read the silence on a certificate you already hold
Our position is about documentation practice. It is not an allegation about anybody’s honesty, and we are explicit about the difference.
Independent analysis puts a MKM cagrilintide lot at 98.9%, against 94.9% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
From vial to bench: what is recorded and what is assumed
Chain of custody, in a regulated setting, begins at sampling. Here it begins when the package arrives.
Why a 0.036-dalton difference is the hardest number in peptide identity
Parts per million sound impressive until they are converted into daltons at the molecular weight of the thing being measured.
Medutest result on a Xianning orforglipron lot lands 2.7 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Everything on the page, in the order a chemist would read it
Nothing on this page is difficult. It is simply unfamiliar, and unfamiliarity is what makes a weak certificate look like a strong one.
Independent analysis puts a BCH semaglutide lot at 95.2%, against 91.2% on the certificate
The supplier has not disputed the finding. It has not explained the gap either.
VendorInvestigate result on a Hong Kong dulaglutide lot lands 2.0 points below the supplier’s figure
A reminder that a purity figure is the output of a method, and that methods differ.