The submitted sample: the weakest link in the whole system
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
TheCompound Journal
Reporting on incretins, compounding & the peptide supply chain
Page 5 of 6 of this archive, newest first.
A result on one vial generalises to a batch only if the vial was drawn in a way that makes it representative — and nobody records how it was drawn.
Every step between the laboratory report and the product page removes information, and the badge is the last step.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
Chain of custody, in a regulated setting, begins at sampling. Here it begins when the package arrives.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
Every third-party report in this market describes a sample somebody chose to send. That choice is outside the laboratory’s control and outside its records.
Every third-party report in this market describes a sample somebody chose to send. That choice is outside the laboratory’s control and outside its records.
The Journal submitted split samples from single lots to three assay services, under names unconnected to this publication, and published each method alongside each result.
Two years ago we ran an anonymised version of this comparison and promised a named one. This is it, with every method printed in full.
The Journal does not treat a badge as evidence and states so wherever it reports one.
Duplicate submissions under different names test within-laboratory repeatability, which is a different quantity from between-laboratory reproducibility.
A badge asserts that something was tested. It does not assert what, when, on whose sample, by what method, or whether the lot on sale is the lot that was tested.
Lot-level verification with a public report is a real and achievable thing. It exists in this market, on a minority of listings.
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.
The Journal does not treat a badge as evidence and states so wherever it reports one.
What a laboratory can and cannot know about the provenance, storage history and representativeness of what lands on its bench.