STEP 5 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The archive — 2024
Page 53 of 68 of this archive, newest first.
Inspectors cite Halvard & Pike Apothecary of Portland, Maine over sterility assurance
The observation that closes a facility is rarely the dramatic one.
What the new Germany guidance says about stopping
The evidence base is thin and the document says so, which is to its credit.
Soft ionisation: the twenty-year-old trick that made peptide identity routine
A brief and unromantic tour of the interface between a liquid sample and a vacuum.
What the trials adjudicated, and how
The features that should prompt urgent assessment, stated once and plainly.
STEP 5 extension data: what happens after the trial stops
A design note rather than a result: what the comparator was, and what that permits you to conclude.
The 28-day notice: how a compounding wind-down works in Canada
The document is four pages. Three of them are about dates.
From the floor in Shenzhen: 10 posters, one theme
Reported from the sessions, and from the two hours afterwards.
Why two wavelengths on one run would settle several arguments
Non-chromophoric components — counter-ions, salts, some excipients — contribute mass to the vial and nothing at all to the chromatogram.
The three-times-upper-limit convention, and where it came from
Asymptomatic pancreatic enzyme elevation is common on treatment and is not pancreatitis. The distinction is clinical, not biochemical.
Shanghai export categories for peptide intermediates were quietly renamed
Follow the resin, not the catalogue.
Germany pharmacy body issues counselling standards for exenatide initiation
The evidence base is thin and the document says so, which is to its credit.
The relabeller trading as Vantris Bio enters a consent decree and stops sterile preparation
The observation that closes a facility is rarely the dramatic one.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Diminishing returns, quantified
The ceiling in this class is anatomical: the same receptor populations that suppress appetite provoke nausea, and they saturate together.
Who signed this, and what did they undertake by signing it
What the Journal asks when a document arrives unsigned, and what the answers have been.
A supplier suspends shipping to Mexico after 23 consecutive customs detentions
The route did not close because of a rule about peptides.
What a 27% rise in coupling-reagent prices does to a 15 mg vial
Follow the resin, not the catalogue.
Holograms, QR codes and other things that are not verification
Reported from the analysis, not from a warning notice.
Denmark health authority warns on falsified semaglutide pens
Reported from the analysis, not from a warning notice.
How a correct calculation becomes a wrong dose
Almost every case involves a change — a new vial, a new syringe size, a new supplier — carried forward with an old number.
HbA1c and its lag: what a result three months old is telling you
HbA1c integrates roughly three months of glycaemia with the most recent weeks weighted most heavily. Almost every misreading of it is a misreading of that weighting.
Twelve things a real certificate has, and what their absence means
The header identifies the batch, the table records the tests, and the footer says who is answerable. Two of the three are usually incomplete.
TRIUMPH-3 misses on a secondary endpoint the coverage has not mentioned
A design note rather than a result: what the comparator was, and what that permits you to conclude.
Mexico declines to reimburse dulaglutide outside a specialist service
Efficacy was never the question in this appraisal. Duration of treatment was.
The quiet end of the relabeller trading as Vantris Bio
A proper account of an operation that existed, and of what closing it cost.
What TRIUMPH-3 tells us about maintenance, and what it does not
A survey of the maintenance evidence, which is shorter than the survey of the withdrawal evidence.
What a 33% rise in coupling-reagent prices does to a 20 mg vial
Follow the resin, not the catalogue.
Portugal caps tirzepatide prescribing to 5 specialist centres
Efficacy was never the question in this appraisal. Duration of treatment was.
The consolidator trading as Meridian Freight Partners closes after 7 years
A proper account of an operation that existed, and of what closing it cost.