Chain of custody, and where it begins
The condition on arrival is recorded by some services and not others, and it is one of the more informative lines in a report.
Nikolaj Brandvold
Page 3 of 7 of this archive, newest first.
Archive — page 3
123 piecesMedutest result on a Suzhou semaglutide lot lands 4.3 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
Medutest result on a Shanghai mazdutide lot lands 1.2 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
The substudies, read properly: who was scanned, when, and with what
The composition data comes from imaging substudies enrolling a few score participants at selected sites. It is the best evidence available and it is thin.
What VendorInvestigate would need in order to certify sterility, and why it does not
We asked all four services what they can determine, on what timescale, at what price, and under what accreditation. The answers are printed in full.
Janoshik result on a Chengdu cagrilintide lot lands 1.8 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
Independent analysis puts a QSC liraglutide lot at 99.2%, against 97.6% on the certificate
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
What twenty companies say about storage, and what they have measured
Storage instructions in this market are close to uniform and almost never accompanied by the study that would justify them. Uniformity is a sign of convention, not of…
Independent analysis puts a GL Biochem liraglutide lot at 96.0%, against 93.9% on the certificate
A reminder that a purity figure is the output of a method, and that methods differ.
How to read the silence on a certificate you already hold
Our position is about documentation practice. It is not an allegation about anybody’s honesty, and we are explicit about the difference.
Independent analysis puts a FGP retatrutide lot at 97.1%, against 95.4% on the certificate
The result is unremarkable. What the report omits is not.
PeptideMeter result on a Hong Kong mazdutide lot lands 1.4 points below the supplier’s figure
The Journal submitted the sample and paid for the analysis. The vendor was told in advance.
The ionisation line on a report is the most informative line on it
The ionisation method determines the charge states you see, the adducts you must account for, and the modifications you might destroy in the process.
Janoshik result on a Nantong mazdutide lot lands 0.9 points below the supplier’s figure
The result is unremarkable. What the report omits is not.
Janoshik result on a Wuxi semaglutide lot lands 2.4 points below the supplier’s figure
The supplier has not disputed the finding. It has not explained the gap either.
Independent analysis puts a SGN orforglipron lot at 96.1%, against 93.2% on the certificate
The result is unremarkable. What the report omits is not.
Twenty-eight days is a number from somebody else’s product
Every degradation pathway accelerates by orders of magnitude on reconstitution, because the solvent that lyophilisation removed is the reagent most of them need.
One measurement, twenty companies, forty compounds
The Journal has read several hundred certificates from twenty companies. The number is almost always there; the method behind it almost never is.
Resolution, tailing, repeatability: the arithmetic before the result
Matching a retention time against a standard is evidence of consistency, not proof of identity. Two different species can elute at the same time on one method.
What counts as total, and who decided
We work through a single chromatogram twice, under two integration conventions, and show where the difference comes from.